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ISBER provides the following tools to the biobanking community:

Self-Assessment Tool (SAT) for Repositories

Assists repository operators in determining how well their repository follows the ISBER Best Practices for Repositories.  Participants receive an individualized report which includes:

  • Final Score - represents the percent compliance with the ISBER Best Practices
  • Questions of Concern - includes questions which most contributed to the overall score.

The SAT is free to ISBER members!

Biorepository Proficiency Testing (PT) Program

(Registration closed until May 2018)

Allows laboratories working with biospecimens to compare their performance to that of other expert laboratories from different sectors all over the world.  PT works as an external quality assessment tool to verify the accuracy, precision and efficiency to laboratories' processing and testing methods.

ISBER members receive discounted PT registration!

Pre-Analytical Biorepository External Quality Assessment (EQA) Survey

Allows participants to benchmark their pre-analytical practices to other biorepositories.  Participants receive and individualized report which includes the results and statistics obtained by all biorepositories who have participated.

The EQA Survey is free to the biorepository community!

International Repository Locator (IRL)

The International Repository Locator (IRL) is an initiative by ISBER to help investigators locate biospecimen and data repositories by developing a directory of repository information that can be searched online. The International Repository Locator  seeks to increase the profile of research and biobanking activities being supported by individual repositories amongst key global stakeholders including scientific societies, researchers, funding bodies, governments, consortia and private industry.
The IRL can be found at and it is free for any biobank to register and free to access for researchers. The IRL collaborates with other organizations that are maintaining catalog of repositories to facilitate global sharing of specimens and data.

 The IRL WG works also closely together with the ISBER Rare Disease WG to encourage participants the Rare Disease WG, or other RD group to register their repositories in the IRL.

Standard Pre-Analytical Code (SPREC)

Identifies and records the main pre-analytical factors that may have impact on the integrity of sampled clinical fluids and solid biospecimens and their simple derivatives during collection, processing and storage.

SPREC is free to the biorepository community!

Biospecimen Stability Testing Calculator (STABCALC)

Determines sample stability, including freeze-thaw stability and storage stability.  STABCALC facilitates stability studies performed by biobanks on different types of biospecimens by identifying potential variabilities in pre-analytical procedures.

STABCALC is free to the biorepository community!

Neurological Disease Metadata

Access metadata related to the biorepository level, the collection level and the individual sample level. Housed in a RedCap server, this tool has been configured in the scope of neurological disease collections, but can be used for other disease collections too.

The Neurological Disease Metadata Database is free to the biorepository community!



As part of its efforts to support biospecimen quality and standardisation, IBBL (Integrated BioBank of Luxembourg) recently launched, a new online tool allowing scientists to validate the quality of their biological samples and improve the reproducibility of their biomedical research.

The tool, which builds on the work of the ISBER Biospecimen Science Working Group, is a user-friendly free of charge application assisting researchers to identify and select the most relevant quality control (QC) assays for a given biospecimen type, thus verifying its fitness-for-purpose for research utilization. Through a few easy steps, users can input the origin, type and sub-type of their samples (e.g. fluid biospecimens, nucleic acids, cells or tissue). The tool subsequently provides a clear suggestion of the most suitable assays. The primary goal of is to raise awareness among the scientific community on the importance of quality control and promote the use of QC assays.  This will ultimately contribute to the translation of research findings into medical practice and meaningful health outcomes for patients. The tool can be accessed through the dedicated webpage

These materials contain information prepared by the International Society for Biological and Environmental Repositories (ISBER) for the international repository community. Although due care has been used in the preparation of these materials, ISBER makes no representation or warranty, express or implied that it is free from errors or omissions, or that it is exhaustive, and expressly disclaims all warranties, including but not limited to, warranties as to the information’s quality or fitness for a particular purpose. The information contained herein is not intended to supplant the judgment of qualified professionals. ISBER and its directors, officers, employees, members, representatives, and agents accept no liability for any loss, cost, expense, injury, or damages, whether direct, indirect, incidental, consequential, special, or other, arising from the application of the information contained in these materials for any use. The accuracy of the information contained herein is subject to changes in circumstances after the time of publication. ISBER accepts no responsibility for the accuracy and reliability of information provided by third parties. Further, ISBER accepts no responsibility for the accuracy and reliability of these materials after language translation.

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