|Biospecimen Stability Testing Calculator|
Use the Biospecimen Stability Testing Calculator (STABCALC) to examine protein stability in body fluids
There is a strong interest of biobank end-users in research for new disease markers. For this purpose, biospecimens are commonly stored for many years in biobanks in order to relate biomarker levels to long-term clinical outcome measures at follow-up. Research is often hampered by variability in pre-analytical procedures, which is an importance source of variation in study outcomes.
One important variability factor is time: collection time, processing time or long-term storage time. The impact of this time can be assessed by short- or long-term stability studies. The new ISBER Biobanking for Neurodegenerative Diseases Working Group presents standardized tools to perform stability studies and examine biomarker stability in biospecimens, e.g., body fluids.
The Biospecimen Stability Testing SOP and Calculator Tool (STABCALC) has been developed by the JPND BIOMARKAPD and JPND Biobanking Working Group projects, and is being made available to the community by ISBER. The tool will facilitate stability studies performed by biobanks on different types of biospecimens.
Click here to read the Biospecimen Stability Testing SOP (read this first)
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